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Researchers accidentally discover broad-spectrum antibiotic without resistance

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Scientists at the University of California have discovered a unique compound called COE2-2hexyl that can be used as a broad-spectrum antibiotic. The researchers were originally working on a project to create a device  for the US Army that would charge cell phones in field conditions using energy derived from bacterial cells. But they discovered that COE2-2hexyl had the ability to kill all the bacterial microorganisms they tested, including those that are resistant to other antibiotics.

Unique Mechanism of Action

According to Professor Michael Meehan, one of the researchers involved in the study, COE2-2hexyl was found to be effective against bacterial microorganisms, which was surprising because they expected it to be toxic to human cells like bleach. The compound works by disrupting numerous bacterial functions and affecting the bacterial membrane, which makes it different from most drugs that target a specific microbial function. This unique mechanism of action gives it a broad-spectrum antibacterial effect, and the low level of bacterial resistance is encouraging. 

Potential to be a New Universal Therapy

The discovery of COE2-2hexyl is significant because it could help address the growing problem of antibiotic resistance. Resistance often occurs due to irrational use of antibiotics or violation of the dosage regimen, so it is important that such drugs are prescribed only by doctors and only in cases where it is justified. Antibiotics have saved millions of lives for almost 100 years, but the threat of antibiotic resistance can bring us back to the times when people died of bacterial pneumonia. COE2-2hexyl has the potential to be a new universal therapy against microbial resistant pathogens, which could help save countless lives.

The discovery of COE2-2hexyl is a major breakthrough in the fight against antibiotic-resistant bacteria. While further research is needed to ensure that the drug is safe for humans, COE2-2hexyl has the potential to be a new universal therapy against microbial resistant pathogens, which could help save countless lives.

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